Background:

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Applications:

ELISA, WB, IHC

Name of antibody:

MAP2K6

Immunogen:

Fusion protein of human MAP2K6

Full name:

mitogen-activated protein kinase kinase 6

Synonyms：

MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3

SwissProt:

P52564

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

37 kDa

WB Positive control:

Mouse muscle tissue

WB Recommended dilution:

500-2000